I-MASK+ Prevention & Early Outpatient Treatment Protocol for COVID-19

PREVENTION PROTOCOL lvermectin1 Prevention for high risk individuals 0.2 mg/kg per dose (take with or after meals) — one dose today, repeat after 48 hours, then one dose weekly*

Post COVID-19 exposure prevention2 0.2 mg/kg per dose (take with or after meals)  — one dose today, repeat after 48 hours*
Vitamin D3 1,000–3,000 IU/day
Vitamin C 500–1,000 mg twice a day
Quercetin 250 mg/day Zinc 30–40 mg/day
Melatonin 6 mg before bedtime (causes drowsiness)

Below you can download the I-MASK+ Prevention & Early Outpatient Treatment Protocol for COVID-19 with guidance on the timing and doses of each component medication. Further below please find more information on the I-MASK+ Protocol.

The I-MASK+ Protocol complements our  MATH+ Hospital Treatment Protocol for Covid-19 from March 2020, which is intended for hospitalized patients. Both are physiologic-based combination treatment regimens developed by leaders in critical care medicine. All component medicines are FDA-approved, inexpensive, readily available and have been used for decades with well-established safety profiles. In October 2020, we added  ivermectin as a core medication in the prevention and treatment of COVID-19.

The protocol document is available in several languages (see below) – more translations are available  here. This is not a medical advice, but a recommendation – please consult your doctor, share the information on this website with her/him, and listen. Please review our  Disclaimers!

Please check this page regularly for updates – new medications may be added and/or dose changes to existing medications may be made as further scientific studies emerge.


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