American Journal of Epidemiology & Public Health – COVID-19 Vaccination would be more Hazardous than Disease itself in 30 Out of 58 Countries –

American Journal of Epidemiology | Oxford Academic

The following is an excerpt from a paper. You can download and read it in full here: AJEPH-ID45 – COVID-19 Vaccination would be more Hazardous than Disease itself in 30 Out of 58 Countries


COVID-19 damaged severely worldwide, and many researchers
have been searching and developing eff ective treatments and vaccines
to control SARS-CoV-2. Pfi zer vaccine and Moderna vaccine are
renowned COVID-19 vaccines which use nanoparticle-encapsulated
mRNA (BNT162b2 or mRNA-1273, respectably), and vaccines
of Johnson & Johnson and AstraZeneca use replication-defective
adenovirus vector (human adenovirus or simian adenovirus,
respectably) [1]. Eff ectiveness of protecting COVID-19 infection was
known as 95% by Pfi zer vaccine [2], 94.1% by Moderna vaccine [3],
90% by the 1st dose and 100% by the 2nd dose of Johnson & Johnson
COVID-19 vaccines [4], and 70.4% by AstraZeneca (58.9% against
asymptomatic infection) [5]. In the long-run, all of these vaccines
introduce S1 subunit of the SARS-CoV-2 spike protein, which contains
the Receptor Binding Domain (RBD) that is able to bind ACE2 [6],
into the human body whether by nanoparticle-encapsulated mRNA
or by adenovirus vector and help to make antibodies to the S1 subunit
of the coronavirus. Existing data suggested that COVID-19 vaccines
might be instrumental in protecting lives and reducing spread of the
disease: it is well suggested that the benefits of vaccines outweigh the
risks [7].

Here are caveats.

In experimental mice, S1 subunit of the SARSCoV-2 spike protein easily penetrated BBB (blood-brain barrier) to
elicit inflammatory changes and S1 toxicity in the brain [8], which
could cause encephalitis, respiratory difficulties, and anosmia
in humans [9], and S1 subunit was distributed in the lung of the
experimental mice [8], which could be related with a cytokine storm
in humans. Circulating S1 subunit of the COVID-19 spike protein,
which was found in the brain and heart, might cause multifocal
microvascular injury in the brain parenchyma, dysfunctions of
Vesicular Monoamine Transporter 2 (VMAT2) [10] and/or of
olfactory bulbs, and/or of myocardium to cause myocarditis, myocyte
necrosis (11/14, 78.6%), and myocardial infarction (3/14, 21.4%) in
experimental mice [11] Above problems, that are related not with
intact SARS-CoV-2 but with only S1 subunit of spike protein of
SARS-CoV-2, were not evaluated in the safety trials of COVID-19
vaccines. Nor Vaccine-associated Th rombocytopenia, which caused a
death of the 56-year-old Florida doctor and several dozen of VAERS
(Vaccine Adverse Event Reporting System) reports, were studied or
expected in the safety trials. Nor did the safety trials expect those
incidental deaths of elderly aft er COVID-19 vaccinations even they
survived and recovered from previous COVID-19 [12]. Nor any
vaccine trials expected that coincidental 12,400 cases of positive
conversion of COVID-19 aft er COVID-19 vaccinations [13]. Millions
of soldiers received COVID-19 vaccinations because they had an
oath to follow orders, and many of them had PTSD (Post-Traumatic
Stress Disorders) before vaccinations. Chronic PTSD persons were
known to have excessive immune responses aft er vaccinations and
conversely, persons who have high levels of infl ammatory cytokines
have a tendency to get PTSD aft er a trauma [14]. Th is means that
PTSD could be occurred aft er COVID-19 vaccinations, for example
a person cried aft er a COVID-19 vaccination as “Th ey’ve Killed
God; I Can’t Feel God; My Soul is dead” [15]. In addition, not all
vaccine-related events might be identifi ed by the vaccine safety tests,
and VAERS did not enclose more than 1% of the real occurrences
of vaccine-associated adverse events [16]. Because there have been
contracts that COVID-19 vaccines companies should be immune
from any liabilities for any possible injures from the COVID-19
vaccinations, nations are advised to take care of persons with vaccineassociated injuries, disabilities, and PTSD patients.
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